Product Data Sheet
SMU-C409
Catalog No. A35394
SMU-C409 is a Toll-like receptor 1/2 (TLR1/2) agonist, exhibiting an EC50 of 65 nM in HEK-Blue hTLR2 cells. It activates the TLR1/2–MyD88–NF-κB signaling pathway, leading to increased secretion of pro-inflammatory cytokines TNF-α and IL-1β, which promotes robust immune cell activation. With low toxicity observed in vitro, SMU-C409 serves as a valuable tool for cancer immunotherapy research.
Chemical Information
| Catalog Num | A35394 |
|---|---|
| M. Wt | 395.54 |
| Formula | C21H21N3OS2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3113739-61-7 |
| Synonyms | |
| SMILES | CC(C)C(C1=C(NC(NC2=C3C=CC=NC3=CC=C2)=S)SC4=C1CCC4)=O |
Biological Activity
| Description | SMU-C409 is a Toll-like receptor 1/2 (TLR1/2) agonist, exhibiting an EC50 of 65 nM in HEK-Blue hTLR2 cells. It activates the TLR1/2–MyD88–NF-κB signaling pathway, leading to increased secretion of pro-inflammatory cytokines TNF-α and IL-1β, which promotes robust immune cell activation. With low toxicity observed in vitro, SMU-C409 serves as a valuable tool for cancer immunotherapy research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
