Product Data Sheet
TLR7 agonist 17
Catalog No. A35397
TLR7 Agonist 17 is a potent agonist of Toll-like receptor 7 (TLR7), exhibiting EC50 values of 12 nM for human TLR7 and 17 nM for mouse TLR7. This compound demonstrates significant anticancer activity, making it valuable for research applications targeting immune modulation and cancer immunotherapy. Its ability to activate TLR7 pathways provides insights into potential therapeutic strategies for harnessing the immune system in oncology.
Chemical Information
| Catalog Num | A35397 |
|---|---|
| M. Wt | 483.61 |
| Formula | C25H37N7O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2410517-32-5 |
| Synonyms | |
| SMILES | NC1=NC(N[C@H](CCO)CCC)=C(N(CC2=C(OC)C=C(CNC3CCOCC3)C=C2)N=C4)C4=N1 |
Biological Activity
| Description | TLR7 Agonist 17 is a potent agonist of Toll-like receptor 7 (TLR7), exhibiting EC50 values of 12 nM for human TLR7 and 17 nM for mouse TLR7. This compound demonstrates significant anticancer activity, making it valuable for research applications targeting immune modulation and cancer immunotherapy. Its ability to activate TLR7 pathways provides insights into potential therapeutic strategies for harnessing the immune system in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
