Product Data Sheet
TLR7 agonist 20
Catalog No. A35411
TLR7 Agonist 20 is an imidazoquinoline analogue that functions as a potent agonist for the Toll-like receptor 7 (TLR7), exhibiting an EC50 value of 0.23 μM for human TLR7. This compound demonstrates significant adjuvant effects on antibody responses, notably enhancing spike antibody levels and promoting a robust T helper 1 (Th1) immune response characterized by increases in IgG2b, IgG2c, and IgG1 production. TLR7 Agonist 20 is suitable for applications in immunological research and the development of vaccine adjuvants.
Chemical Information
| Catalog Num | A35411 |
|---|---|
| M. Wt | 360.45 |
| Formula | C22H24N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3029695-00-6 |
| Synonyms | |
| SMILES | CCCCC1=NC2=C(C3=CC=CC=C3N=C2N)N1CC4=CC=C(C=C4)CO |
Biological Activity
| Description | TLR7 Agonist 20 is an imidazoquinoline analogue that functions as a potent agonist for the Toll-like receptor 7 (TLR7), exhibiting an EC50 value of 0.23 μM for human TLR7. This compound demonstrates significant adjuvant effects on antibody responses, notably enhancing spike antibody levels and promoting a robust T helper 1 (Th1) immune response characterized by increases in IgG2b, IgG2c, and IgG1 production. TLR7 Agonist 20 is suitable for applications in immunological research and the development of vaccine adjuvants. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
