Product Data Sheet
Esculeoside A
Catalog No. A35469
Esculeoside A is a spirosolane-type steroidal alkaloid glycoside that primarily targets NF-κB and Nrf2/Keap1 signaling pathways. This compound exhibits significant cardioprotective and hypoglycemic properties, regulating glucose metabolism and modulating lipid profiles. Research applications include the study of diabetic cardiomyopathy, type 2 diabetes, atopic dermatitis, tumors, and atherosclerotic diseases. Additionally, Esculeoside A inhibits dendritic cell maturation and T-cell proliferation, and exhibits anti-tumor activity against breast cancer and melanoma cells.
Chemical Information
| Catalog Num | A35469 |
|---|---|
| M. Wt | 1270.36 |
| Formula | C58H95NO29 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 532387-86-3 |
| Synonyms | |
| SMILES | C[C@@H]1[C@@]2([C@H](C[C@@H](CN2)CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)OC(C)=O)O[C@]4([H])[C@@]1([H])[C@@]5([C@@]([C@@]6([H])[C@]([C@@]7([C@@](C[C@H](CC7)O[C@@H]8O[C@@H]([C@@H]([C@@H]([C@H]8O)O)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O[C@H]%10[C@@H]([C@H]([C@@H](CO%10)O)O)O)O[C@@H]%11O[C@@H]([C@H]([C@@H]([C@H]%11O)O)O)CO)CO)([H])CC6)C)([H])CC5)([H])C4)C |
Biological Activity
| Description | Esculeoside A is a spirosolane-type steroidal alkaloid glycoside that primarily targets NF-κB and Nrf2/Keap1 signaling pathways. This compound exhibits significant cardioprotective and hypoglycemic properties, regulating glucose metabolism and modulating lipid profiles. Research applications include the study of diabetic cardiomyopathy, type 2 diabetes, atopic dermatitis, tumors, and atherosclerotic diseases. Additionally, Esculeoside A inhibits dendritic cell maturation and T-cell proliferation, and exhibits anti-tumor activity against breast cancer and melanoma cells. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
