Product Data Sheet
TLR7/8 agonist 9
Catalog No. A35488
TLR7/8 Agonist 9 is a potent agonist of Toll-like receptors 7 and 8, exhibiting EC50 values of 40 nM and 23 nM, respectively, for human TLR7 and TLR8. This compound demonstrates anti-tumor activity and enhances the efficacy of PD-1/PD-L1 blockade, making it a valuable tool for cancer immunotherapy research. It is suitable for studies investigating immune modulation and therapeutic strategies in oncological applications.
Chemical Information
| Catalog Num | A35488 |
|---|---|
| M. Wt | 366.46 |
| Formula | C20H26N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2649170-17-0 |
| Synonyms | |
| SMILES | NC1=NC(NCCOC)=C2C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)=N1 |
Biological Activity
| Description | TLR7/8 Agonist 9 is a potent agonist of Toll-like receptors 7 and 8, exhibiting EC50 values of 40 nM and 23 nM, respectively, for human TLR7 and TLR8. This compound demonstrates anti-tumor activity and enhances the efficacy of PD-1/PD-L1 blockade, making it a valuable tool for cancer immunotherapy research. It is suitable for studies investigating immune modulation and therapeutic strategies in oncological applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
