Product Data Sheet
TLR7/8 antagonist 1
Catalog No. A35490
TLR7/8 Antagonist 1 is a potent antagonist of Toll-like receptors 7 and 8, exhibiting IC50 values of 3.91 μM and 2.19 μM, respectively. This imidazoquinoline derivative is instrumental in modulating immune responses and serves as a valuable tool in research applications targeting infectious diseases, cancer, and autoimmune disorders. Its unique mechanism of action enables the exploration of TLR-mediated pathways, contributing to the development of novel immunomodulatory therapies.
Chemical Information
| Catalog Num | A35490 |
|---|---|
| M. Wt | 417.50 |
| Formula | C24H27N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2901020-63-9 |
| Synonyms | |
| SMILES | COC(C1=CC2=NC(N)=C3N=C(N(C3=C2C=C1)CC4=CC=C(CN)C=C4)CC(C)C)=O |
Biological Activity
| Description | TLR7/8 Antagonist 1 is a potent antagonist of Toll-like receptors 7 and 8, exhibiting IC50 values of 3.91 μM and 2.19 μM, respectively. This imidazoquinoline derivative is instrumental in modulating immune responses and serves as a valuable tool in research applications targeting infectious diseases, cancer, and autoimmune disorders. Its unique mechanism of action enables the exploration of TLR-mediated pathways, contributing to the development of novel immunomodulatory therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
