Product Data Sheet
TLR8 agonist 10
Catalog No. A35501
TLR8 Agonist 10 is a selective agonist targeting Toll-like receptor 8 (TLR8), demonstrating an EC50 of 0.019 μM in human cells. This compound activates TLR8-mediated signaling pathways, functioning as a latency-reversing agent that reactivates latent HIV-1 reservoirs. Additionally, TLR8 Agonist 10 enhances the activity of innate cytotoxic natural killer cells, allowing for targeted effects on HIV-infected CD4+ T cells. This reagent is valuable for research focused on HIV-1 infection and immune modulation.
Chemical Information
| Catalog Num | A35501 |
|---|---|
| M. Wt | 326.48 |
| Formula | C20H30N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2796210-93-8 |
| Synonyms | |
| SMILES | CCCCNC1=CC(CC2=CC=C(C=C2)CN(C)C)=C(N=C1N)C |
Biological Activity
| Description | TLR8 Agonist 10 is a selective agonist targeting Toll-like receptor 8 (TLR8), demonstrating an EC50 of 0.019 μM in human cells. This compound activates TLR8-mediated signaling pathways, functioning as a latency-reversing agent that reactivates latent HIV-1 reservoirs. Additionally, TLR8 Agonist 10 enhances the activity of innate cytotoxic natural killer cells, allowing for targeted effects on HIV-infected CD4+ T cells. This reagent is valuable for research focused on HIV-1 infection and immune modulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
