Product Data Sheet
QS-21-Api
Catalog No. A35523
QS-21-Api is a potent NLRP3 activator that functions as an immunostimulatory saponin, enhancing vaccine efficacy as an adjuvant. It stimulates both Th2 humoral and Th1 cell-mediated immune responses by acting on antigen presenting cells (APCs) and T cells. Through the activation of the NLRP3 inflammasome, QS-21-Api prompts the release of caspase-1 dependent cytokines, including IL-1β and IL-18, making it a valuable tool for research in immunology and vaccine development.
Chemical Information
| Catalog Num | A35523 |
|---|---|
| M. Wt | 1990.13 |
| Formula | C92H148O46 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 141256-04-4 |
| Synonyms | Stimulon |
| SMILES | O=C([C@]1(CCC(C)(C)C2)[C@]2([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O[C@@](O[C@H](C(O)=O)[C@@H](O)[C@@H]6O[C@@](OC[C@@H](O)[C@@H]7O)([H])[C@@H]7O)([H])[C@@H]6O[C@]([C@@H]([C@@H](O)[C@H]8O)O)([H])O[C@@H]8CO)[C@@]5(C)C=O)C)[C@]3(C)C[C@H]1O)O[C@H](O[C@H](C)[C@H](OC(C[C@@H](O)C[C@]([C@@H](C)CC)([H])OC(C[C@@H](O)C[C@]([C@@H](C)CC)([H])O[C@@H]9O[C@@H](CO)[C@H](O)[C@H]9O)=O)=O)[C@@H]%10O)[C@@H]%10O[C@@](O[C@@H](C)[C@H](O[C@@](OC[C@@H](O)[C@@H]%11O[C@@](OC[C@]%12(O)CO)([H])[C@@H]%12O)([H])[C@@H]%11O)[C@H]%13O)([H])[C@@H]%13O |
Biological Activity
| Description | QS-21-Api is a potent NLRP3 activator that functions as an immunostimulatory saponin, enhancing vaccine efficacy as an adjuvant. It stimulates both Th2 humoral and Th1 cell-mediated immune responses by acting on antigen presenting cells (APCs) and T cells. Through the activation of the NLRP3 inflammasome, QS-21-Api prompts the release of caspase-1 dependent cytokines, including IL-1β and IL-18, making it a valuable tool for research in immunology and vaccine development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
