Product Data Sheet
IIIM-1270
Catalog No. A35599
IIIM-1270 is a selective NLRP3 inflammasome inhibitor that effectively reduces the release of IL-1β in mouse macrophages (J774A.1 cells) with an IC50 of 3.5 μM. This compound significantly lowers the protein expression levels of mature IL-1β, making it a valuable tool for investigations into inflammatory pathways. IIIM-1270 is ideal for research applications focused on understanding the role of the NLRP3 inflammasome in various disease models related to inflammation.
Chemical Information
| Catalog Num | A35599 |
|---|---|
| M. Wt | 233.29 |
| Formula | C12H11NO2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 4818-19-3 |
| Synonyms | |
| SMILES | CC1=CC=C(/C=C2SC(NC/2=O)=O)C(C)=C1 |
Biological Activity
| Description | IIIM-1270 is a selective NLRP3 inflammasome inhibitor that effectively reduces the release of IL-1β in mouse macrophages (J774A.1 cells) with an IC50 of 3.5 μM. This compound significantly lowers the protein expression levels of mature IL-1β, making it a valuable tool for investigations into inflammatory pathways. IIIM-1270 is ideal for research applications focused on understanding the role of the NLRP3 inflammasome in various disease models related to inflammation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
