Product Data Sheet
Fc 11a-2
Catalog No. A35602
Fc 11a-2 is a benzimidazole compound that functions as a potent inhibitor of the NLRP3 inflammasome. It effectively reduces the activation of caspase-1, leading to decreased secretion of pro-inflammatory cytokines IL-1b and IL-18. This compound has demonstrated protective effects in model systems, including the prevention of Dextran sulfate sodium-induced murine experimental colitis, making it valuable for research in inflammation and related diseases.
Chemical Information
| Catalog Num | A35602 |
|---|---|
| M. Wt | 236.31 |
| Formula | C16H16N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 960119-75-9 |
| Synonyms | |
| SMILES | CC1=CC=C2N(CC)C(C3=CC=CC=C3)=NC2=C1 |
Biological Activity
| Description | Fc 11a-2 is a benzimidazole compound that functions as a potent inhibitor of the NLRP3 inflammasome. It effectively reduces the activation of caspase-1, leading to decreased secretion of pro-inflammatory cytokines IL-1b and IL-18. This compound has demonstrated protective effects in model systems, including the prevention of Dextran sulfate sodium-induced murine experimental colitis, making it valuable for research in inflammation and related diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
