Product Data Sheet
MS-II-124
Catalog No. A35604
MS-II-124 is a potent and selective inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 0.12 μM. This compound exhibits significant anti-inflammatory and immunomodulatory activities, making it a valuable tool for research applications related to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Its targeted inhibition of NLRP3 positions MS-II-124 as a promising candidate for elucidating the roles of inflammasomes in various inflammatory diseases.
Chemical Information
| Catalog Num | A35604 |
|---|---|
| M. Wt | 543.05 |
| Formula | C28H28ClFN2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3037332-85-4 |
| Synonyms | |
| SMILES | ClC1=CC=C(OCCC)C(CN(CCC2=CC=C(S(=O)(NCC#C)=O)C=C2)C(C3=CC=C(F)C=C3)=O)=C1 |
Biological Activity
| Description | MS-II-124 is a potent and selective inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 0.12 μM. This compound exhibits significant anti-inflammatory and immunomodulatory activities, making it a valuable tool for research applications related to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Its targeted inhibition of NLRP3 positions MS-II-124 as a promising candidate for elucidating the roles of inflammasomes in various inflammatory diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
