Product Data Sheet

NLRP3-IN-26

Catalog No. A35642

main product photo
NLRP3-IN-26 is a specific inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 0.13 μM. This compound is useful for studying the role of NLRP3 in inflammatory processes and can be applied in models of DSS-induced colitis to elucidate its impact on intestinal inflammation and immune responses.
Chemical Information
Catalog NumA35642
M. Wt597.12
FormulaC31H33ClN2O6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2927413-30-5
Synonyms
SMILESO=C(N(C1CC2=CC=C(S(=O)(NCCC)=O)C=C2C1)CC3=CC(Cl)=CC=C3OCCOC)C4=CC5=C(C=CC=C5)O4
Biological Activity
DescriptionNLRP3-IN-26 is a specific inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 0.13 μM. This compound is useful for studying the role of NLRP3 in inflammatory processes and can be applied in models of DSS-induced colitis to elucidate its impact on intestinal inflammation and immune responses.
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