Product Data Sheet
Kaempferol-7-O-rhamnoside
Catalog No. A35687
Kaempferol-7-O-rhamnoside is a potent inhibitor of the PD-1/PD-L1 pathway and an agonist of the farnesoid X receptor (FXR). It exhibits cardioprotective properties by targeting the AMPKα1 signaling pathway, significantly enhancing mRNA expression of AMPKα1 in H9c2 cardiomyocytes. Additionally, Kaempferol-7-O-rhamnoside effectively reverses acetaminophen-induced reductions in glutathione levels and mitigates reactive oxygen species production in L02 cells. This compound demonstrates potential applications in research related to heart failure and oxidative stress.
Chemical Information
| Catalog Num | A35687 |
|---|---|
| M. Wt | 432.38 |
| Formula | C21H20O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 20196-89-8 |
| Synonyms | |
| SMILES | O=C1C(O)=C(C2=CC=C(O)C=C2)OC3=CC(O[C@H]4[C@@H]([C@@H]([C@H]([C@H](C)O4)O)O)O)=CC(O)=C13 |
Biological Activity
| Description | Kaempferol-7-O-rhamnoside is a potent inhibitor of the PD-1/PD-L1 pathway and an agonist of the farnesoid X receptor (FXR). It exhibits cardioprotective properties by targeting the AMPKα1 signaling pathway, significantly enhancing mRNA expression of AMPKα1 in H9c2 cardiomyocytes. Additionally, Kaempferol-7-O-rhamnoside effectively reverses acetaminophen-induced reductions in glutathione levels and mitigates reactive oxygen species production in L02 cells. This compound demonstrates potential applications in research related to heart failure and oxidative stress. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
