Product Data Sheet

PD-1/PD-L1-IN 5 TFA

Catalog No. A35709

main product photo
PD-1/PD-L1-IN 5 TFA is a potent inhibitor of the PD-1/PD-L1 protein-protein interaction, with an IC50 of ≤100 nM. This compound is beneficial for research applications focused on immune checkpoint modulation, particularly in the context of cancer immunotherapy. By blocking the PD-1/PD-L1 pathway, it aids in the investigation of T-cell activation and tumor immune evasion mechanisms.
Chemical Information
Catalog NumA35709
M. Wt
FormulaC22H18N4O3S.xC2HF3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2170209-52-4
Synonyms
SMILESN#CC1=C(NC(C2=NC3=C(CNCC3)S2)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4.OC(C(F)(F)F)=O.[x]
Biological Activity
DescriptionPD-1/PD-L1-IN 5 TFA is a potent inhibitor of the PD-1/PD-L1 protein-protein interaction, with an IC50 of ≤100 nM. This compound is beneficial for research applications focused on immune checkpoint modulation, particularly in the context of cancer immunotherapy. By blocking the PD-1/PD-L1 pathway, it aids in the investigation of T-cell activation and tumor immune evasion mechanisms.
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.