Product Data Sheet

PD-L1-IN-5

Catalog No. A35722

main product photo
PD-L1-IN-5 is a potent inhibitor of programmed death-ligand 1 (PD-L1), exhibiting an IC50 value of 785.6 nM. This compound demonstrates significant anti-tumor activity in vivo, making it a valuable tool for cancer research. PD-L1-IN-5 is utilized in studies focusing on immune checkpoint regulation and therapeutic strategies aimed at enhancing anti-tumor immunity.
Chemical Information
Catalog NumA35722
M. Wt763.25
FormulaC40H44ClFN4O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2597056-85-2
Synonyms
SMILESOC1CCN(CCCOC2=CC=CC(C3=CC=CC(COC4=C(Cl)C=C(CN[C@@H](C(OCC)=O)CO)C(OCC5=CC6=NON=C6C=C5)=C4)=C3F)=C2)CC1
Biological Activity
DescriptionPD-L1-IN-5 is a potent inhibitor of programmed death-ligand 1 (PD-L1), exhibiting an IC50 value of 785.6 nM. This compound demonstrates significant anti-tumor activity in vivo, making it a valuable tool for cancer research. PD-L1-IN-5 is utilized in studies focusing on immune checkpoint regulation and therapeutic strategies aimed at enhancing anti-tumor immunity.
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SHIPPING AND STORAGE
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