Product Data Sheet

CYP51/PD-L1-IN-4

Catalog No. A35767

main product photo
CYP51/PD-L1-IN-4 is a potent dual-target inhibitor of CYP51 and PD-L1, demonstrating IC50 values of 0.17 μM and 0.021 μM, respectively. This compound exhibits significant antifungal activity and is effective against drug-resistant fungal strains in vitro. CYP51/PD-L1-IN-4 is suitable for research applications focused on fungal infections and the interplay between fungal pathogens and immune checkpoint regulation.
Chemical Information
Catalog NumA35767
M. Wt470.56
FormulaC28H30N4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3032391-34-4
Synonyms
SMILESCC1=C(C2=CC=CC=C2)C=CC=C1COC3=CC(CN[C@@H](C(OCC)=O)CN4C=NC=N4)=CC=C3
Biological Activity
DescriptionCYP51/PD-L1-IN-4 is a potent dual-target inhibitor of CYP51 and PD-L1, demonstrating IC50 values of 0.17 μM and 0.021 μM, respectively. This compound exhibits significant antifungal activity and is effective against drug-resistant fungal strains in vitro. CYP51/PD-L1-IN-4 is suitable for research applications focused on fungal infections and the interplay between fungal pathogens and immune checkpoint regulation.
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