Nogapendekin alfa (his tag)
Catalog No. A35880

Nogapendekin alfa (his tag) is a soluble protein subunit of a human interleukin-15 variant, acting as a potent superagonist of IL-15. It enhances the proliferation and survival of immune cells, making it valuable for various immuno-oncology studies. In combination with Inbakicept, Nogapendekin alfa forms the IL-15 cytokine-antibody fusion protein N-803, which has demonstrated the ability to reduce tumor burden through the activation of natural killer (NK) cells and CD8+ T cells. This reagent is instrumental in research applications targeting cancer immunotherapy and immune response modulation.
Chemical Information
| Catalog Num | A35880 |
|---|---|
| M. Wt | 13.91 kDa |
| Formula | |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1622189-43-8 |
| Synonyms | IL-15N72D |
| SMILES | [Nogapendekin alfa (his tag)] |
Biological Activity
| Description | Nogapendekin alfa (his tag) is a soluble protein subunit of a human interleukin-15 variant, acting as a potent superagonist of IL-15. It enhances the proliferation and survival of immune cells, making it valuable for various immuno-oncology studies. In combination with Inbakicept, Nogapendekin alfa forms the IL-15 cytokine-antibody fusion protein N-803, which has demonstrated the ability to reduce tumor burden through the activation of natural killer (NK) cells and CD8+ T cells. This reagent is instrumental in research applications targeting cancer immunotherapy and immune response modulation. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


