Product Data Sheet
Xanthomicrol
Catalog No. A35930
Xanthomicrol is a monoamine oxidase (MAO) inhibitor derived from the resin of the Chinese bellflower (Scrophulariaceae family). It exhibits significant anti-inflammatory and anti-tumor activities, with IC50 values of 0.88 and 1.69 μg/mL in HL60 and K562 cells, respectively. Xanthomicrol has been shown to reduce both iNOS protein and mRNA levels, as well as COX-2 protein levels. Additionally, it diminishes the production of the pro-inflammatory cytokine IL-1β and upregulates the antioxidant enzyme HO-1, making it a valuable tool for research in inflammatory and cancer-related studies.
Chemical Information
| Catalog Num | A35930 |
|---|---|
| M. Wt | 344.32 |
| Formula | C18H16O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 16545-23-6 |
| Synonyms | |
| SMILES | COC1=C(OC)C(OC)=C2C(C(C=C(C3=CC=C(O)C=C3)O2)=O)=C1O |
Biological Activity
| Description | Xanthomicrol is a monoamine oxidase (MAO) inhibitor derived from the resin of the Chinese bellflower (Scrophulariaceae family). It exhibits significant anti-inflammatory and anti-tumor activities, with IC50 values of 0.88 and 1.69 μg/mL in HL60 and K562 cells, respectively. Xanthomicrol has been shown to reduce both iNOS protein and mRNA levels, as well as COX-2 protein levels. Additionally, it diminishes the production of the pro-inflammatory cytokine IL-1β and upregulates the antioxidant enzyme HO-1, making it a valuable tool for research in inflammatory and cancer-related studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
