Product Data Sheet
Dimethyl diacetyl cystinate
Catalog No. A35982
Dimethyl diacetyl cystinate (DACDM) is a potent NF-κB inhibitor that modulates inflammation by shifting the intracellular redox balance towards an oxidized state. This compound increases the levels of oxidized glutathione (GSSG) and competes with activated NF-κB for binding sites on DNA, thus inhibiting the production of pro-inflammatory cytokines such as IL-1κ. DACDM is a valuable reagent for studies related to UVB-induced skin inflammation and various oxidative stress-related diseases.
Chemical Information
| Catalog Num | A35982 |
|---|---|
| M. Wt | 352.43 |
| Formula | C12H20N2O6S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 32381-28-5 |
| Synonyms | DACDM |
| SMILES | CC(N[C@H](C(OC)=O)CSSC[C@H](NC(C)=O)C(OC)=O)=O |
Biological Activity
| Description | Dimethyl diacetyl cystinate (DACDM) is a potent NF-κB inhibitor that modulates inflammation by shifting the intracellular redox balance towards an oxidized state. This compound increases the levels of oxidized glutathione (GSSG) and competes with activated NF-κB for binding sites on DNA, thus inhibiting the production of pro-inflammatory cytokines such as IL-1κ. DACDM is a valuable reagent for studies related to UVB-induced skin inflammation and various oxidative stress-related diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
