Product Data Sheet
Acutissimalignan B
Catalog No. A36004
Acutissimalignan B is a bioactive compound recognized for its role as an anti-inflammatory agent. It effectively reduces the mRNA expression of key inflammatory cytokines, including inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6). Additionally, Acutissimalignan B inhibits the phosphorylation of IκBα and the nuclear translocation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) p65, thereby demonstrating potential utility in neuroinflammation research and related disease models.
Chemical Information
| Catalog Num | A36004 |
|---|---|
| M. Wt | 356.37 |
| Formula | C20H20O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1005390-47-5 |
| Synonyms | |
| SMILES | COC(C=C1/C=C(C(OC2)=O)\[C@@H]2CC3=CC(OC)=C(C=C3)O)=C(C=C1)O |
Biological Activity
| Description | Acutissimalignan B is a bioactive compound recognized for its role as an anti-inflammatory agent. It effectively reduces the mRNA expression of key inflammatory cytokines, including inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6). Additionally, Acutissimalignan B inhibits the phosphorylation of IκBα and the nuclear translocation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) p65, thereby demonstrating potential utility in neuroinflammation research and related disease models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
