Product Data Sheet
HB-0017
Catalog No. A36012
HB-0017 is a humanized IgG1κ monoclonal antibody that specifically targets interleukin-17A (IL-17A). This antibody effectively inhibits IL-6 secretion induced by IL-17A with an IC50 value of 2.09 nM. HB-0017 has demonstrated significant efficacy in reducing ear thickness in a psoriasis-like mouse model induced by Imiquimod, as well as alleviating inflammation in models of IL-17A-induced arthritis and air pouch inflammation.
Chemical Information
| Catalog Num | A36012 |
|---|---|
| M. Wt | |
| Formula | |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2790610-50-1 |
| Synonyms | |
| SMILES | N/A |
Biological Activity
| Description | HB-0017 is a humanized IgG1κ monoclonal antibody that specifically targets interleukin-17A (IL-17A). This antibody effectively inhibits IL-6 secretion induced by IL-17A with an IC50 value of 2.09 nM. HB-0017 has demonstrated significant efficacy in reducing ear thickness in a psoriasis-like mouse model induced by Imiquimod, as well as alleviating inflammation in models of IL-17A-induced arthritis and air pouch inflammation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
