Product Data Sheet
Ro26-4550 TFA
Catalog No. A36027
Ro26-4550 TFA is a low micromolar antagonist of the interleukin-2 (IL-2) and IL-2 receptor alpha (IL-2Rα) interaction, exhibiting an IC50 value of 3 μM. This compound serves as a valuable tool for investigating the IL-2 signaling pathway, making it relevant for studies in immunology and cancer research. Its ability to inhibit IL-2 signaling can aid in the understanding of immune responses and the development of therapeutic strategies targeting IL-2 mediated pathways.
Chemical Information
| Catalog Num | A36027 |
|---|---|
| M. Wt | 560.56 |
| Formula | C28H31F3N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217448-66-2 |
| Synonyms | |
| SMILES | O=C(OC)[C@H](CC1=CC=C(C#CC2=CC=CC=C2)C=C1)NC(C[C@@H]3CN(C(N)=N)CCC3)=O.O=C(O)C(F)(F)F |
Biological Activity
| Description | Ro26-4550 TFA is a low micromolar antagonist of the interleukin-2 (IL-2) and IL-2 receptor alpha (IL-2Rα) interaction, exhibiting an IC50 value of 3 μM. This compound serves as a valuable tool for investigating the IL-2 signaling pathway, making it relevant for studies in immunology and cancer research. Its ability to inhibit IL-2 signaling can aid in the understanding of immune responses and the development of therapeutic strategies targeting IL-2 mediated pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
