Product Data Sheet
Trimegestone
Catalog No. A36334
Trimegestone acts as a progesterone receptor antagonist, exhibiting a high binding affinity with an IC50 value of 3.3 nM for the rat progesterone receptor. This 19-norpregnane progestin enhances alkaline phosphatase activity, with an EC50 of 0.1 nM, while displaying minimal effects on luciferase activity. Additionally, Trimegestone possesses weak antiandrogenic properties due to its low affinity for the androgen receptor. This compound is valuable in research focusing on contraception and menopausal syndrome investigations.
Chemical Information
| Catalog Num | A36334 |
|---|---|
| M. Wt | 342.47 |
| Formula | C22H30O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 74513-62-5 |
| Synonyms | RU 27987 |
| SMILES | C[C@@]12[C@](CC[C@]2(C)C([C@@H](O)C)=O)([H])[C@@]3([H])C(CC1)=C4C(CC3)=CC(CC4)=O |
Biological Activity
| Description | Trimegestone acts as a progesterone receptor antagonist, exhibiting a high binding affinity with an IC50 value of 3.3 nM for the rat progesterone receptor. This 19-norpregnane progestin enhances alkaline phosphatase activity, with an EC50 of 0.1 nM, while displaying minimal effects on luciferase activity. Additionally, Trimegestone possesses weak antiandrogenic properties due to its low affinity for the androgen receptor. This compound is valuable in research focusing on contraception and menopausal syndrome investigations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
