Product Data Sheet

STAT6-IN-10

Catalog No. A36476

main product photo
STAT6-IN-10 is a potent inhibitor of signal transducer and activator of transcription 6 (STAT6), exhibiting an EC50 of 0.002 μM. This compound effectively inhibits the secretion of CCL17 in peripheral human whole blood with an IC50 of 0.095 μM, making it a valuable tool for studying inflammatory responses. STAT6-IN-10 is applicable in research focused on dermatological and respiratory conditions, providing insights into therapeutic interventions targeting these pathways.
Chemical Information
Catalog NumA36476
M. Wt507.59
FormulaC29H29N7O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3092076-19-9
Synonyms
SMILESO=C(C1=NN(C)C2=CC=C(C3=CC=C(C4=NC=CN4C)C=C3)C=C12)NCC5=CC=C(NC(N(C)C)=O)C=C5
Biological Activity
DescriptionSTAT6-IN-10 is a potent inhibitor of signal transducer and activator of transcription 6 (STAT6), exhibiting an EC50 of 0.002 μM. This compound effectively inhibits the secretion of CCL17 in peripheral human whole blood with an IC50 of 0.095 μM, making it a valuable tool for studying inflammatory responses. STAT6-IN-10 is applicable in research focused on dermatological and respiratory conditions, providing insights into therapeutic interventions targeting these pathways.
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