5,15-Diphenylporphyrin
Catalog No. A36502

5,15-Diphenylporphyrin acts as a STAT3 antagonist by binding specifically to the SH2 domain of the STAT3 protein. This interaction disrupts the pTyr-SH2 binding, consequently inhibiting STAT3 dimerization, nuclear translocation, and DNA binding activity. As a result, 5,15-Diphenylporphyrin reduces the expression of genes associated with cancer cell proliferation and survival. This compound is valuable for research in the development of novel anticancer therapies.
Chemical Information
| Catalog Num | A36502 |
|---|---|
| M. Wt | 462.54 |
| Formula | C32H22N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 22112-89-6 |
| Synonyms | 5,15-DPP |
| SMILES | C1(/C2=CC=CC=C2)=C3C=CC(/C=C4C=C/C(N/4)=C(C5=CC=CC=C5)/C(C=C/6)=NC6=C/C7=CC=C1N7)=N/3 |
Biological Activity
| Description | 5,15-Diphenylporphyrin acts as a STAT3 antagonist by binding specifically to the SH2 domain of the STAT3 protein. This interaction disrupts the pTyr-SH2 binding, consequently inhibiting STAT3 dimerization, nuclear translocation, and DNA binding activity. As a result, 5,15-Diphenylporphyrin reduces the expression of genes associated with cancer cell proliferation and survival. This compound is valuable for research in the development of novel anticancer therapies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


