Product Data Sheet

Stafib-2

Catalog No. A36508

main product photo
Stafib-2 is a selective inhibitor of the transcription factor STAT5b, demonstrating an IC50 of 82 nM specifically for STAT5b and 1.7 μM for STAT5a. This compound is critical for studies exploring the role of STAT5b in various biological processes, including cell proliferation and survival. Although Stafib-2 exhibits limited cell permeability, it remains a valuable tool for researchers investigating signaling pathways associated with STAT5b in cancer and other diseases.
Chemical Information
Catalog NumA36508
M. Wt644.46
FormulaC28H26N2O12P2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2097938-74-2
Synonyms
SMILESO=C(NC1=CC=C(OC2=CC=CC=C2)C=C1)C3=CC=C(OCC(NCC4=CC=C(OP(O)(O)=O)C(OP(O)(O)=O)=C4)=O)C=C3
Biological Activity
DescriptionStafib-2 is a selective inhibitor of the transcription factor STAT5b, demonstrating an IC50 of 82 nM specifically for STAT5b and 1.7 μM for STAT5a. This compound is critical for studies exploring the role of STAT5b in various biological processes, including cell proliferation and survival. Although Stafib-2 exhibits limited cell permeability, it remains a valuable tool for researchers investigating signaling pathways associated with STAT5b in cancer and other diseases.
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SHIPPING AND STORAGE
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