STAT6 degrader-3
Catalog No. A36526

STAT6 degrader-3 is a highly potent and selective degrader of the signal transducer and activator of transcription 6 (STAT6), exhibiting a DC50 of <1 nM. This compound facilitates the targeted degradation of STAT6, making it instrumental in investigating Type 2 immune responses and associated allergic mechanisms in various biological contexts. Its precise action allows for in-depth studies into the modulation of immune pathways linked to inflammatory diseases.
Chemical Information
| Catalog Num | A36526 |
|---|---|
| M. Wt | 851.99 |
| Formula | C47H53N11O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3077464-19-5 |
| Synonyms | |
| SMILES | O=C(N(C)C)C1=CC2=C(C3=CC=C(N4CCN(CCCC5=CC=C6C(N(C)C(N6C7C(NC(CC7)=O)=O)=O)=C5)CC4)C=C3)C=C(C8=CCCN(C8)C(CCN9N=NC=C9)=O)C=C2N1 |
Biological Activity
| Description | STAT6 degrader-3 is a highly potent and selective degrader of the signal transducer and activator of transcription 6 (STAT6), exhibiting a DC50 of <1 nM. This compound facilitates the targeted degradation of STAT6, making it instrumental in investigating Type 2 immune responses and associated allergic mechanisms in various biological contexts. Its precise action allows for in-depth studies into the modulation of immune pathways linked to inflammatory diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


