Product Data Sheet

Galiellalactone

Catalog No. A36534

main product photo
Galiellalactone is a selective inhibitor of STAT3 signaling, exhibiting an IC50 value of 250-500 nM. This small, non-toxic, and non-mutagenic fungal metabolite is relevant for research involving castration-resistant prostate cancer, providing insights into the mechanisms of cancer biology and therapeutic resistance. Its specificity towards STAT3 makes it a valuable tool for studying the role of this pathway in various cellular processes.
Chemical Information
Catalog NumA36534
M. Wt194.23
FormulaC11H14O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.133613-71-5
Synonyms
SMILESO=C1C2=C[C@@H](C)C[C@@]3([H])CC[C@@]([C@@]23O)([H])O1
Biological Activity
DescriptionGaliellalactone is a selective inhibitor of STAT3 signaling, exhibiting an IC50 value of 250-500 nM. This small, non-toxic, and non-mutagenic fungal metabolite is relevant for research involving castration-resistant prostate cancer, providing insights into the mechanisms of cancer biology and therapeutic resistance. Its specificity towards STAT3 makes it a valuable tool for studying the role of this pathway in various cellular processes.
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