Product Data Sheet
STAT3 HiBiT degrader 1
Catalog No. A36564
STAT3 HiBiT Degrader 1 is a potent compound that selectively targets the signal transducer and activator of transcription 3 (STAT3) for degradation. It demonstrates a DC50 value of less than 0.05 μM in A549 cells, highlighting its efficacy in reducing STAT3 levels. This degrader offers valuable tools for studying the role of STAT3 in cancer and other diseases, facilitating the investigation of pathways regulated by this transcription factor.
Chemical Information
| Catalog Num | A36564 |
|---|---|
| M. Wt | 1263.21 |
| Formula | C58H63F4N10O14PS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2767166-30-1 |
| Synonyms | |
| SMILES | FC(F)(P(O)(O)=O)C1=CC(C=C(C(N[C@H]2CN(C(OC)=O)CC[C@@H]3N([C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N4CCC(CCC#CC5=CC(N(C)C(N6C7C(NC(CC7)=O)=O)=O)=C6C=C5)CC4)=O)CC8=CC=C(F)C(F)=C8)=O)=O)CC3)C2=O)=O)S9)=C9C=C1 |
Biological Activity
| Description | STAT3 HiBiT Degrader 1 is a potent compound that selectively targets the signal transducer and activator of transcription 3 (STAT3) for degradation. It demonstrates a DC50 value of less than 0.05 μM in A549 cells, highlighting its efficacy in reducing STAT3 levels. This degrader offers valuable tools for studying the role of STAT3 in cancer and other diseases, facilitating the investigation of pathways regulated by this transcription factor. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
