Product Data Sheet
PROTAC STAT3 degrader-2
Catalog No. A36599
PROTAC STAT3 degrader-2 is a highly selective degrader targeting the STAT3 protein with a DC50 value of 3.54 μM in Molm-16 cells. This compound is designed for cancer research applications, facilitating the targeted degradation of STAT3 to investigate its role in tumorigenesis. Additionally, PROTAC STAT3 degrader-2 features an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, providing versatility in experimental designs.
Chemical Information
| Catalog Num | A36599 |
|---|---|
| M. Wt | 1172.13 |
| Formula | C59H60F2N9O13P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2429877-78-9 |
| Synonyms | |
| SMILES | O=C1C2=C(C#CCCCCCC(N3C[C@@H](C(N4[C@@](CC[C@H]4C(N[C@@H](CCC(N)=O)C(NC(C5=CC=CC=C5)C6=CC=CC=C6)=O)=O)([H])CC3)=O)NC(C7=CC8=CC(C(F)(F)P(O)(O)=O)=CC=C8N7)=O)=O)C=CC=C2C(N1C9C(NC(CC9)=O)=O)=O |
Biological Activity
| Description | PROTAC STAT3 degrader-2 is a highly selective degrader targeting the STAT3 protein with a DC50 value of 3.54 μM in Molm-16 cells. This compound is designed for cancer research applications, facilitating the targeted degradation of STAT3 to investigate its role in tumorigenesis. Additionally, PROTAC STAT3 degrader-2 features an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, providing versatility in experimental designs. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
