Product Data Sheet
GPR34 receptor antagonist 3
Catalog No. A36644
GPR34 receptor antagonist 3 is a selective antagonist of the GPR34 receptor, with an IC50 value of 0.680 μM. This compound effectively inhibits ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent manner, demonstrating minimal cytotoxicity. GPR34 receptor antagonist 3 is valuable for research into the modulation of sensory signaling pathways and has shown antisensory activity in mouse models of neuropathic pain.
Chemical Information
| Catalog Num | A36644 |
|---|---|
| M. Wt | 515.98 |
| Formula | C30H26ClNO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3049949-94-9 |
| Synonyms | |
| SMILES | O=C(COC1=CC=C(C2=CC(Cl)=CC=C2)C=C1)N[C@H](C(O)=O)CC(C=C3)=CC=C3OCC4=CC=CC=C4 |
Biological Activity
| Description | GPR34 receptor antagonist 3 is a selective antagonist of the GPR34 receptor, with an IC50 value of 0.680 μM. This compound effectively inhibits ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent manner, demonstrating minimal cytotoxicity. GPR34 receptor antagonist 3 is valuable for research into the modulation of sensory signaling pathways and has shown antisensory activity in mouse models of neuropathic pain. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
