Product Data Sheet
OR-1855
Catalog No. A36650
OR-1855 is an active metabolite of Levosimendan that primarily targets myometrial contractility. It demonstrates anti-inflammatory properties by inhibiting IL-1β-induced reactive oxygen species (ROS) formation and NAD(P)H oxidase-dependent superoxide radical generation in human umbilical vein endothelial cells (HUVECs). Furthermore, OR-1855 suppresses IL-1β-induced phosphorylation of key signaling molecules, including p38 MAPK, ERK1/2, c-Jun, and JNK. This compound is valuable for research focused on inflammation and related biological processes.
Chemical Information
| Catalog Num | A36650 |
|---|---|
| M. Wt | 203.25 |
| Formula | C11H13N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 101328-85-2 |
| Synonyms | |
| SMILES | O=C1C[C@@H](C)C(C2=CC=C(N)C=C2)=NN1 |
Biological Activity
| Description | OR-1855 is an active metabolite of Levosimendan that primarily targets myometrial contractility. It demonstrates anti-inflammatory properties by inhibiting IL-1β-induced reactive oxygen species (ROS) formation and NAD(P)H oxidase-dependent superoxide radical generation in human umbilical vein endothelial cells (HUVECs). Furthermore, OR-1855 suppresses IL-1β-induced phosphorylation of key signaling molecules, including p38 MAPK, ERK1/2, c-Jun, and JNK. This compound is valuable for research focused on inflammation and related biological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
