Product Data Sheet
9(10)-Nitrooleate
Catalog No. A36695
9(10)-Nitrooleate is an Akt activator that enhances enzymatic activity and promotes nitric oxide bioavailability. By inducing the phosphorylation of Akt and ERK1/2, it regulates the multi-site phosphorylation of eNOS and optimizes its interaction with Hsp90, contributing to its vasoprotective effects. Additionally, 9(10)-Nitrooleate activates PPARα, PPARδ, and PPARγ receptors, influencing adipogenesis, glucose uptake, and inflammatory gene expression. Its immunosuppressive properties also inhibit neutrophil migration and cytokine secretion, making it valuable for research on sepsis and related inflammatory conditions.
Chemical Information
| Catalog Num | A36695 |
|---|---|
| M. Wt | 327.46 |
| Formula | C18H33NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1092676-99-7 |
| Synonyms | 9(10)-Nitrated oleic acid |
| SMILES | OC(CCCCCCC/C([N+]([O-])=O)=C\CCCCCCCC)=O.OC(CCCCCCC/C=C([N+]([O-])=O)\CCCCCCCC)=O |
Biological Activity
| Description | 9(10)-Nitrooleate is an Akt activator that enhances enzymatic activity and promotes nitric oxide bioavailability. By inducing the phosphorylation of Akt and ERK1/2, it regulates the multi-site phosphorylation of eNOS and optimizes its interaction with Hsp90, contributing to its vasoprotective effects. Additionally, 9(10)-Nitrooleate activates PPARα, PPARδ, and PPARγ receptors, influencing adipogenesis, glucose uptake, and inflammatory gene expression. Its immunosuppressive properties also inhibit neutrophil migration and cytokine secretion, making it valuable for research on sepsis and related inflammatory conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
