Product Data Sheet
UC-857993
Catalog No. A36732
UC-857993 is a selective inhibitor of the SOS1-Ras interaction, effectively suppressing its catalytic activity with a Kd of 14.7 μM (His6-SOS1cat). This compound also inhibits ERK and Ras activation, demonstrating significant capabilities in reducing the proliferation of mouse embryonic fibroblasts (MEFs). UC-857993 is valuable for research into cancer biology and signaling pathways involving Ras.
Chemical Information
| Catalog Num | A36732 |
|---|---|
| M. Wt | 403.90 |
| Formula | C25H22ClNO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 487001-04-7 |
| Synonyms | |
| SMILES | O=C(C1=CC2=C3N(C(C4=CC=CC=C4Cl)C5C2C=CC5)CC(CC=C6)C6C3=C1)O |
Biological Activity
| Description | UC-857993 is a selective inhibitor of the SOS1-Ras interaction, effectively suppressing its catalytic activity with a Kd of 14.7 μM (His6-SOS1cat). This compound also inhibits ERK and Ras activation, demonstrating significant capabilities in reducing the proliferation of mouse embryonic fibroblasts (MEFs). UC-857993 is valuable for research into cancer biology and signaling pathways involving Ras. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
