Product Data Sheet
20:4 Lyso PI
Catalog No. A36744
20:4 Lyso PI is a selective agonist of the G protein-coupled receptor GPR55, exhibiting a potency with an EC50 value of 10 nM in inducing cell rounding in GPR55-expressing HEK293 cells. This compound activates RhoA, leading to ROCK-dependent cytoskeletal rearrangement, and stimulates the ERK signaling pathway while increasing intracellular free calcium levels. 20:4 Lyso PI is valuable for research into immune diseases and related cellular signaling mechanisms.
Chemical Information
| Catalog Num | A36744 |
|---|---|
| M. Wt | 620.67 |
| Formula | C29H49O12P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1246430-04-5 |
| Synonyms | |
| SMILES | O[C@H]1[C@@H](OP(O)(OC[C@@H](COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)O)=O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O |
Biological Activity
| Description | 20:4 Lyso PI is a selective agonist of the G protein-coupled receptor GPR55, exhibiting a potency with an EC50 value of 10 nM in inducing cell rounding in GPR55-expressing HEK293 cells. This compound activates RhoA, leading to ROCK-dependent cytoskeletal rearrangement, and stimulates the ERK signaling pathway while increasing intracellular free calcium levels. 20:4 Lyso PI is valuable for research into immune diseases and related cellular signaling mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
