Product Data Sheet

ETP-45835 dihydrochloride

Catalog No. A36778

main product photo
ETP-45835 dihydrochloride is a selective inhibitor of Erk2, exhibiting an IC50 value of 18.7 μM. This compound demonstrates significant inhibitory effects on cell proliferation, with an EC50 value of 0.9 μM. ETP-45835 is valuable for research applications focused on cell signaling pathways and the modulation of Erk2 activity in various biological contexts.
Chemical Information
Catalog NumA36778
M. Wt301.21
FormulaC13H18Cl2N4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2136571-30-5
Synonyms
SMILESC1(C2=NNC(C3CCNCC3)=C2)=CC=NC=C1.Cl.Cl
Biological Activity
DescriptionETP-45835 dihydrochloride is a selective inhibitor of Erk2, exhibiting an IC50 value of 18.7 μM. This compound demonstrates significant inhibitory effects on cell proliferation, with an EC50 value of 0.9 μM. ETP-45835 is valuable for research applications focused on cell signaling pathways and the modulation of Erk2 activity in various biological contexts.
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