Product Data Sheet

3-(4-Pyridyl)indole

Catalog No. A36803

main product photo
3-(4-Pyridyl)indole is a selective Rho-kinase (ROCK) inhibitor, exhibiting an IC50 value of 25 μM. This compound is known to effectively inhibit cellular blebbing and promote the dissolution of actin stress fibers, making it a valuable reagent for studying wound healing mechanisms and cytoskeletal dynamics in various biological research applications.
Chemical Information
Catalog NumA36803
M. Wt194.23
FormulaC13H10N2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.7272-84-6
SynonymsRockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout
SMILESC1(C2=CC=NC=C2)=CNC3=C1C=CC=C3
Biological Activity
Description3-(4-Pyridyl)indole is a selective Rho-kinase (ROCK) inhibitor, exhibiting an IC50 value of 25 μM. This compound is known to effectively inhibit cellular blebbing and promote the dissolution of actin stress fibers, making it a valuable reagent for studying wound healing mechanisms and cytoskeletal dynamics in various biological research applications.
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