Product Data Sheet
GSK269962A hydrochloride
Catalog No. A36804
GSK269962A hydrochloride is a potent ROCK inhibitor that selectively targets Rho-associated coiled-coil kinase 1 (ROCK1) and ROCK2, with IC50 values of 1.6 nM and 4 nM, respectively. It exhibits significant anti-inflammatory and vasodilatory properties, making it valuable in research applications focused on vascular biology, cardiovascular diseases, and inflammatory conditions. This compound provides a useful tool for elucidating the role of ROCK signaling in various biological processes.
Chemical Information
| Catalog Num | A36804 |
|---|---|
| M. Wt | 607.06 |
| Formula | C29H31ClN8O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2095432-71-4 |
| Synonyms | GSK 269962 hydrochloride |
| SMILES | CCN1C2=CC(OC3=CC=CC(NC(C4=CC=C(OCCN5CCOCC5)C=C4)=O)=C3)=NC=C2N=C1C6=NON=C6N.Cl |
Biological Activity
| Description | GSK269962A hydrochloride is a potent ROCK inhibitor that selectively targets Rho-associated coiled-coil kinase 1 (ROCK1) and ROCK2, with IC50 values of 1.6 nM and 4 nM, respectively. It exhibits significant anti-inflammatory and vasodilatory properties, making it valuable in research applications focused on vascular biology, cardiovascular diseases, and inflammatory conditions. This compound provides a useful tool for elucidating the role of ROCK signaling in various biological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
