Product Data Sheet
(rac)-AR-13503
Catalog No. A36806
(rac)-AR-13503 is a potent inhibitor of Rho-associated protein kinase (ROCK) and protein kinase C (PKC). It plays a significant role in regulating angiogenesis and enhancing retinal pigment epithelium (RPE) permeability. Additionally, (rac)-AR-13503 has demonstrated the ability to inhibit aberrant neovascularization in the oxygen-induced retinopathy (OIR) model in mice, making it a valuable tool for research in ocular disorders and vascular biology.
Chemical Information
| Catalog Num | A36806 |
|---|---|
| M. Wt | 321.37 |
| Formula | C19H19N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1254032-16-0 |
| Synonyms | (rac)-AR-13324 M1 metabolite |
| SMILES | O=C(C(CN)C1=CC=C(CO)C=C1)NC2=CC3=C(C=C2)C=NC=C3 |
Biological Activity
| Description | (rac)-AR-13503 is a potent inhibitor of Rho-associated protein kinase (ROCK) and protein kinase C (PKC). It plays a significant role in regulating angiogenesis and enhancing retinal pigment epithelium (RPE) permeability. Additionally, (rac)-AR-13503 has demonstrated the ability to inhibit aberrant neovascularization in the oxygen-induced retinopathy (OIR) model in mice, making it a valuable tool for research in ocular disorders and vascular biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
