Product Data Sheet
Sovesudil hydrochloride
Catalog No. A36808
Sovesudil hydrochloride is a highly selective Rho kinase (ROCK) inhibitor that competitively binds to ATP, demonstrating IC50 values of 3.7 nM for ROCK-I and 2.3 nM for ROCK-II. It effectively reduces intraocular pressure (IOP) and is noteworthy for its ability to do so without causing hyperemia. This compound is utilized in research focused on glaucoma and other ocular conditions linked to elevated IOP.
Chemical Information
| Catalog Num | A36808 |
|---|---|
| M. Wt | 443.90 |
| Formula | C23H23ClFN3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2984963-50-8 |
| Synonyms | PHP-201 hydrochloride; AMA0076 hydrochloride |
| SMILES | O=C(C1=CC(C2=CC(C(NC3=C(F)C=NC=C3)=O)=CC=C2CN)=CC=C1)OCCC.[H]Cl |
Biological Activity
| Description | Sovesudil hydrochloride is a highly selective Rho kinase (ROCK) inhibitor that competitively binds to ATP, demonstrating IC50 values of 3.7 nM for ROCK-I and 2.3 nM for ROCK-II. It effectively reduces intraocular pressure (IOP) and is noteworthy for its ability to do so without causing hyperemia. This compound is utilized in research focused on glaucoma and other ocular conditions linked to elevated IOP. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
