Product Data Sheet

ROCK2-IN-8

Catalog No. A36810

main product photo
ROCK2-IN-8 is an orally active inhibitor of Rho-associated protein kinase 2 (ROCK2) with an IC50 of 7.2 nM. This compound is valuable in studies investigating aqueous humor outflow in porcine eyes, as well as the phosphorylation of myosin light chain. Its specificity for ROCK2 makes it a useful tool in exploring the roles of this kinase in various biological processes.
Chemical Information
Catalog NumA36810
M. Wt339.37
FormulaC17H13N3O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.681173-76-2
Synonyms
SMILESO=C(C1OC2=C(OC1)C=CC=C2)NC3=NC(C4=CC=NC=C4)=CS3
Biological Activity
DescriptionROCK2-IN-8 is an orally active inhibitor of Rho-associated protein kinase 2 (ROCK2) with an IC50 of 7.2 nM. This compound is valuable in studies investigating aqueous humor outflow in porcine eyes, as well as the phosphorylation of myosin light chain. Its specificity for ROCK2 makes it a useful tool in exploring the roles of this kinase in various biological processes.
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