Product Data Sheet

LIMK-IN-1

Catalog No. A36815

main product photo
LIMK-IN-1 is a potent inhibitor of LIM-Kinase (LIMK), exhibiting IC50 values of 0.5 nM for LIMK1 and 0.9 nM for LIMK2. This compound is primarily utilized in research related to ocular hypertension and associated glaucoma, contributing to studies aimed at understanding the role of LIMK in these conditions. Its high specificity and efficacy make it a valuable tool for investigating the molecular pathways involved in ocular diseases.
Chemical Information
Catalog NumA36815
M. Wt453.34
FormulaC20H21BrN8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1116571-01-7
Synonyms
SMILESCC1=CNC2=NC=NC(N3C[C@H](C)N(/C(NC4=CC=CC(Br)=C4)=N\C#N)CC3)=C21
Biological Activity
DescriptionLIMK-IN-1 is a potent inhibitor of LIM-Kinase (LIMK), exhibiting IC50 values of 0.5 nM for LIMK1 and 0.9 nM for LIMK2. This compound is primarily utilized in research related to ocular hypertension and associated glaucoma, contributing to studies aimed at understanding the role of LIMK in these conditions. Its high specificity and efficacy make it a valuable tool for investigating the molecular pathways involved in ocular diseases.
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