Product Data Sheet
Centaureidin
Catalog No. A36839
Centaureidin is an orally active anti-inflammatory agent derived from Bidens pilosa, exhibiting an EC50 of 0.9 μg/mL as an IFN-promoter. This compound activates the Rho signaling pathway, resulting in actin and tubulin disassembly, which leads to dendritic retraction and the formation of stress fibers in melanocytes. Centaureidin demonstrates potent inhibitory effects on tumor cell growth and has been shown to significantly reduce paw edema in murine models, highlighting its potential utility in inflammatory and anticancer research.
Chemical Information
| Catalog Num | A36839 |
|---|---|
| M. Wt | 360.31 |
| Formula | C18H16O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 17313-52-9 |
| Synonyms | |
| SMILES | O=C1C(OC)=C(C2=CC(O)=C(OC)C=C2)OC3=CC(O)=C(C(O)=C13)OC |
Biological Activity
| Description | Centaureidin is an orally active anti-inflammatory agent derived from Bidens pilosa, exhibiting an EC50 of 0.9 μg/mL as an IFN-promoter. This compound activates the Rho signaling pathway, resulting in actin and tubulin disassembly, which leads to dendritic retraction and the formation of stress fibers in melanocytes. Centaureidin demonstrates potent inhibitory effects on tumor cell growth and has been shown to significantly reduce paw edema in murine models, highlighting its potential utility in inflammatory and anticancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
