Product Data Sheet
ROCK-IN-4
Catalog No. A36855
ROCK-IN-4 is a selective inhibitor of Rho-associated protein kinase (ROCK), exhibiting the capacity to maintain nitric oxide releasing ability. This compound effectively reversibly depolymerizes F-actin and inhibits mitochondrial respiration in human trabecular meshwork (HTM) cells. ROCK-IN-4 is valuable for research related to glaucoma and ocular hypertension, making it a critical tool for investigating cellular mechanisms involved in these conditions.
Chemical Information
| Catalog Num | A36855 |
|---|---|
| M. Wt | 520.96 |
| Formula | C20H26ClFN4O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2488395-07-7 |
| Synonyms | |
| SMILES | C[C@H]1CN(C(OCCCCO[N+]([O-])=O)=O)CCCN1S(=O)(C2=CC=CC3=C2C(F)=CN=C3)=O.[H]Cl |
Biological Activity
| Description | ROCK-IN-4 is a selective inhibitor of Rho-associated protein kinase (ROCK), exhibiting the capacity to maintain nitric oxide releasing ability. This compound effectively reversibly depolymerizes F-actin and inhibits mitochondrial respiration in human trabecular meshwork (HTM) cells. ROCK-IN-4 is valuable for research related to glaucoma and ocular hypertension, making it a critical tool for investigating cellular mechanisms involved in these conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
