Product Data Sheet

TBCA

Catalog No. A36877

main product photo
TBCA is a selective inhibitor of casein kinase II (CK2), exhibiting an IC50 of 110 nM and a Ki value of 77 nM. This compound demonstrates a significant preference for CK2 over CK1, DYRK1A, and a diverse panel of 27 other kinases. TBCA is valuable for research applications focused on studying the role of CK2 in cellular signaling and disease mechanisms.
Chemical Information
Catalog NumA36877
M. Wt463.74
FormulaC9H4Br4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.934358-00-6
Synonyms
SMILESOC(/C=C/C1=C(C(Br)=C(Br)C(Br)=C1)Br)=O
Biological Activity
DescriptionTBCA is a selective inhibitor of casein kinase II (CK2), exhibiting an IC50 of 110 nM and a Ki value of 77 nM. This compound demonstrates a significant preference for CK2 over CK1, DYRK1A, and a diverse panel of 27 other kinases. TBCA is valuable for research applications focused on studying the role of CK2 in cellular signaling and disease mechanisms.
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