Product Data Sheet
JNJ-6204
Catalog No. A36885
JNJ-6204 is a potent dual inhibitor of Casein Kinase 1 Delta (CSNK1D) and Casein Kinase 1 Epsilon (CSNK1E), with IC50 values of 2.3 nM and 137 nM, respectively. This compound exhibits significant brain penetration, making it a valuable tool for investigating the roles of CSNK1D and CSNK1E in cellular signaling and neurobiology. JNJ-6204 is particularly useful in the study of diseases associated with dysregulated Wnt signaling and circadian rhythm disturbances.
Chemical Information
| Catalog Num | A36885 |
|---|---|
| M. Wt | 370.41 |
| Formula | C19H11D6FN6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2765264-50-2 |
| Synonyms | |
| SMILES | FC1=CC=C(N=C1)C2=NN3C(COC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C3)=C2C4=C5C(NN=C5)=NC=C4 |
Biological Activity
| Description | JNJ-6204 is a potent dual inhibitor of Casein Kinase 1 Delta (CSNK1D) and Casein Kinase 1 Epsilon (CSNK1E), with IC50 values of 2.3 nM and 137 nM, respectively. This compound exhibits significant brain penetration, making it a valuable tool for investigating the roles of CSNK1D and CSNK1E in cellular signaling and neurobiology. JNJ-6204 is particularly useful in the study of diseases associated with dysregulated Wnt signaling and circadian rhythm disturbances. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
