Product Data Sheet
PF-4800567 hydrochloride
Catalog No. A36907
PF-4800567 hydrochloride is a potent and selective inhibitor of casein kinase 1 (CK1), exhibiting an IC50 of 32 nM. It demonstrates over 20-fold selectivity for CK1α when compared to CK1δ, with an IC50 value of 711 nM. This compound is valuable for investigating the distinct roles of these kinases in various signaling pathways, making it an essential tool for research in cellular signaling and kinase-related studies.
Chemical Information
| Catalog Num | A36907 |
|---|---|
| M. Wt | 396.27 |
| Formula | C17H19Cl2N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1391052-28-0 |
| Synonyms | |
| SMILES | NC1=C2C(N(C3CCOCC3)N=C2COC4=CC=CC(Cl)=C4)=NC=N1.[H]Cl |
Biological Activity
| Description | PF-4800567 hydrochloride is a potent and selective inhibitor of casein kinase 1 (CK1), exhibiting an IC50 of 32 nM. It demonstrates over 20-fold selectivity for CK1α when compared to CK1δ, with an IC50 value of 711 nM. This compound is valuable for investigating the distinct roles of these kinases in various signaling pathways, making it an essential tool for research in cellular signaling and kinase-related studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
