Product Data Sheet

CK2-IN-3

Catalog No. A36918

main product photo
CK2-IN-3 is a selective and potent inhibitor of casein kinase 2 (CK2), exhibiting a Kd of 12 nM and IC50 values of 1.51 μM for CK2α and 7.64 μM for CK2α’. This compound demonstrates significant biological activity in suppressing CK2 activity and is primarily utilized in cancer research to explore therapeutic strategies targeting CK2-dependent signaling pathways.
Chemical Information
Catalog NumA36918
M. Wt458.46
FormulaC22H26N4O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2969205-85-2
Synonyms
SMILESO=C(O)C1=CC=C(C2=C3N=C(N(C(OC(C)(C)C)=O)CCOCCO)C=CN3N=C2)C=C1O
Biological Activity
DescriptionCK2-IN-3 is a selective and potent inhibitor of casein kinase 2 (CK2), exhibiting a Kd of 12 nM and IC50 values of 1.51 μM for CK2α and 7.64 μM for CK2α’. This compound demonstrates significant biological activity in suppressing CK2 activity and is primarily utilized in cancer research to explore therapeutic strategies targeting CK2-dependent signaling pathways.
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