Product Data Sheet
CK1-IN-2 hydrochloride
Catalog No. A36925
CK1-IN-2 hydrochloride is a potent inhibitor of casein kinase 1 (CK1), demonstrating IC50 values of 123 nM for CK1a, 19.8 nM for CK1d, 26.8 nM for CK1e, and 74.3 nM for p38a. This compound is valuable for research applications focused on cellular signaling pathways and the modulation of CK1-related processes. Its selective inhibition can help elucidate the role of CK1 in various biological contexts, including cancer and neurodegenerative diseases.
Chemical Information
| Catalog Num | A36925 |
|---|---|
| M. Wt | 345.76 |
| Formula | C17H13ClFN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1383377-49-8 |
| Synonyms | |
| SMILES | O=C1OCC2=NC=CC(C3=CN(C)N=C3C4=CC=C(F)C=C4)=C12.[H]Cl |
Biological Activity
| Description | CK1-IN-2 hydrochloride is a potent inhibitor of casein kinase 1 (CK1), demonstrating IC50 values of 123 nM for CK1a, 19.8 nM for CK1d, 26.8 nM for CK1e, and 74.3 nM for p38a. This compound is valuable for research applications focused on cellular signaling pathways and the modulation of CK1-related processes. Its selective inhibition can help elucidate the role of CK1 in various biological contexts, including cancer and neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
