Product Data Sheet
CK2-IN-11
Catalog No. A36932
CK2-IN-11 is an allosteric inhibitor of Casein Kinase 2 (CK2), exhibiting high selectivity with IC50 values of 19.3 nM for the CK2α2β2 isoform and 15.6 nM for CK2α′2β2. This compound is important for studies involving CK2's role in cellular processes such as proliferation, apoptosis, and signaling pathways. Its potent inhibition makes CK2-IN-11 a valuable tool for research applications focusing on cancer biology and the modulation of CK2-related pathways.
Chemical Information
| Catalog Num | A36932 |
|---|---|
| M. Wt | 776.97 |
| Formula | C23H22Br4Cl2N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2938991-22-9 |
| Synonyms | |
| SMILES | O=C(NCCCCN1C=NC2=C(C(Br)=C(C(Br)=C21)Br)Br)CCC(NCCC3=CC=C(C(Cl)=C3)Cl)=O |
Biological Activity
| Description | CK2-IN-11 is an allosteric inhibitor of Casein Kinase 2 (CK2), exhibiting high selectivity with IC50 values of 19.3 nM for the CK2α2β2 isoform and 15.6 nM for CK2α′2β2. This compound is important for studies involving CK2's role in cellular processes such as proliferation, apoptosis, and signaling pathways. Its potent inhibition makes CK2-IN-11 a valuable tool for research applications focusing on cancer biology and the modulation of CK2-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
